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Steven K Burke Selected Research

Sevelamer (RenaGel)

12/2008Sevelamer restores bone volume and improves bone microarchitecture and strength in aged ovariectomized rats.
9/2006Results of a randomized crossover study comparing once-daily and thrice-daily sevelamer dosing.
7/2006Novel dosage forms and regimens for sevelamer-based phosphate binders.
5/2005Decrease in thoracic vertebral bone attenuation with calcium-based phosphate binders in hemodialysis.
6/2004Determinants of progressive vascular calcification in haemodialysis patients.
11/2003Sevelamer hydrochloride attenuates kidney and cardiovascular calcifications in long-term experimental uremia.
10/2003Sevelamer hydrochloride, a phosphate binder, protects against deterioration of renal function in rats with progressive chronic renal insufficiency.
9/2003The effects of sevelamer and calcium acetate on proxies of atherosclerotic and arteriosclerotic vascular disease in hemodialysis patients.
8/2003Sevelamer hydrochloride prevents ectopic calcification and renal osteodystrophy in chronic renal failure rats.
4/2003Meta-analysis of the effect of sevelamer on phosphorus, calcium, PTH, and serum lipids in dialysis patients.
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Steven K Burke Research Topics

Disease

8Hyperphosphatemia
01/2022 - 04/2003
7Arteriovenous Fistula
03/2022 - 04/2013
7Chronic Renal Insufficiency
01/2022 - 10/2003
5Vascular Calcification
05/2005 - 02/2002
5Chronic Kidney Failure (Chronic Renal Failure)
11/2003 - 02/2002
4Fistula
03/2022 - 08/2014
3Renal Insufficiency (Renal Failure)
09/2006 - 08/2003
3Secondary Hyperparathyroidism
05/2005 - 09/2002
3Hypercalcemia (Milk Alkali Syndrome)
09/2004 - 07/2002
2Peripheral Arterial Disease
04/2016 - 12/2014
2Kidney Diseases (Kidney Disease)
08/2014 - 01/2008
2Fibrosis (Cirrhosis)
08/2003 - 09/2002
1Anemia
01/2022
1Hypoxia (Hypoxemia)
01/2022
1Pathologic Constriction (Stenosis)
08/2014
1alpha 1-Antitrypsin Deficiency (alpha 1 Antitrypsin Deficiency)
01/2012
1Hyperparathyroidism
01/2008
1Arteriosclerosis
01/2008
1Bone Diseases (Bone Disease)
09/2004
1Nephrocalcinosis
11/2003
1Proteinuria
11/2003
1Uremia
11/2003
1Vascular Diseases (Vascular Disease)
09/2003
1Chronic Kidney Disease-Mineral and Bone Disorder (Renal Rickets)
08/2003
1Cardiovascular Diseases (Cardiovascular Disease)
04/2003
1Hyperplasia
09/2002
1Aortic Aneurysm (Aneurysm, Aortic)
02/2002
1Coronary Artery Disease (Coronary Atherosclerosis)
02/2002
1Myocardial Infarction
02/2002

Drug/Important Bio-Agent (IBA)

12Sevelamer (RenaGel)FDA Link
12/2008 - 07/2002
11Phosphates (Orthophosphate)IBA
01/2022 - 07/2002
8cholesterol-binding proteinIBA
03/2022 - 01/2012
8Phosphorus (Red Phosphorus)IBA
01/2008 - 09/2002
8CalciumIBA
05/2005 - 02/2002
7Pancreatic Elastase (Elastase)IBA
03/2022 - 01/2012
3MineralsIBA
12/2008 - 02/2002
3Calcium Carbonate (Limestone)FDA Link
11/2003 - 09/2002
2Pharmaceutical PreparationsIBA
03/2022 - 01/2019
2SolutionsIBA
03/2022 - 01/2019
2SaltsIBA
05/2005 - 09/2003
2LipidsIBA
06/2004 - 04/2003
2calcium phosphateIBA
11/2003 - 09/2002
1Prolyl-Hydroxylase InhibitorsIBA
01/2022
1vadadustatIBA
01/2022
1IronIBA
01/2022
1ElastinIBA
01/2016
1Phenobarbital (Luminal)FDA Link
12/2014
1Dihydrotachysterol (AT 10)IBA
08/2014
1alpha 1-Antitrypsin (alpha 1 Antitrypsin)IBA
01/2012
1Biological ProductsIBA
01/2008
1Vitamin DFDA LinkGeneric
01/2008
1Dosage Forms (Dosage Form)IBA
07/2006
1PolymersIBA
05/2005
1CreatinineIBA
11/2003
1calcium acetate (Phoslo)FDA LinkGeneric
09/2003
1AlbuminsIBA
09/2003
1AdenineFDA LinkGeneric
08/2003

Therapy/Procedure

11Renal Dialysis (Hemodialysis)
03/2022 - 02/2002
1Surgical Amputation (Amputations)
04/2016
1Therapeutics
01/2012
1Renal Replacement Therapy (Therapies, Renal Replacement)
09/2006